Cambridge biotech tracker · Charlestown

Solid Biosciences

Listed on Nasdaq as SLDB, filed under SEC industry code 2836 (biological products). Fiscal year ends in December. Numbers below are from the company’s own SEC filings through Q2 '26.

Cash & investments
$378M
Q2 '26 · Jun 29, 2026
Burn per quarter
$46.7M
avg. operating cash flow, 4 qtrs
Runway
2.0 yrs
24 to 36 months
Net loss
$54.8M
Q2 '26
R&D expense
$44.3M
77% of opex
Raised, last 4 qtrs
+$294M
net financing cash flow

Cash & investments

Quarter-end balance

Cash & investments$0$250M$500MQ3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26$378M$381M

Operating cash flow

Per quarter; below zero is burn

Operating cash flow−$100M−$50M$0K$0Q3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26−$52.6M−$53.6M

R&D expense

Per quarter

R&D expense$0$25M$50MQ3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26$44.3M$46.1M

The controller’s read

What the filings say.

Generated from the numbers above using the same questions I ask when I open a client’s books: how long the cash lasts, what is driving the gap between loss and burn, and where the accounting judgment sits.

Get this read on your company

About 2.0 years of runway

Cash and investments of $378M at Q2 '26 against an average operating cash burn of $46.7M per quarter over the last four reported quarters runs out around June 2028. More than two years of runway means the finance conversation is about deployment, not survival.

Cash position up $207M since Q3 '24

Net financing inflows of $294M over the last four quarters, from equity, debt, or ATM sales, more than covered operating burn. The balance is the number the board watches; the trend is the number the auditors watch.

R&D is 77% of operating expenses

$44.3M of R&D against $57.4M of total operating expenses in Q2 '26, with G&A at $13.1M. For a clinical-stage company, the accounting questions live inside that R&D line: CRO and CMC accruals, milestone recognition, and what gets capitalized versus expensed under ASC 730.

Accumulated deficit of $1.07B

Total losses since inception. It is also roughly the size of the net operating loss carryforward the tax provision has to track, subject to Section 382 limits after each ownership change.

Quarterly detail, eight quarters
QuarterCash & inv.Op. cash flowNet lossR&DG&ARevenueStock compFinancing
Q3 '24 · Sep 29, 24$171M−$23.7M−$32.7M$27.3M$7.9M$3.0M$3.3M
Q4 '24 · Dec 30, 24$149M−$29.6M−$42.6M$30.8M$9.1M$3.8M$6.9M
Q1 '25 · Mar 30, 25$307M−$31.9M−$39.3M$30.9M$9.1M$3.3M$190M
Q2 '25 · Jun 29, 25$268M−$37.4M−$39.5M$32.4M$9.3M$3.1M−$1.6M
Q3 '25 · Sep 29, 25$236M−$33.5M−$45.8M$38.9M$9.2M$3.9M$1.2M
Q4 '25 · Dec 30, 25$188M−$53.6M−$49.8M$38.1M$11.3M$6.5M$5.1M
Q1 '26 · Mar 30, 26$381M−$47.2M−$56.7M$46.1M$11.2M$5.2M$239M
Q2 '26 · Jun 29, 26$378M−$52.6M−$54.8M$44.3M$13.1M$5.6M$48.5M

Source: SEC EDGAR XBRL company facts, latest filed value for each period. Fourth quarters are derived from annual less nine-month figures; quarterly cash flows are derived from year-to-date amounts. Not investment advice. If a figure disagrees with the filing, the filing is right.