Cambridge biotech tracker · Boston

Bicara Therapeutics

Listed on Nasdaq as BCAX, filed under SEC industry code 2834 (pharmaceutical preparations). Fiscal year ends in December. Numbers below are from the company’s own SEC filings through Q2 '26.

Cash & investments
$497M
Q2 '26 · Jun 29, 2026
Burn per quarter
$33.7M
avg. operating cash flow, 4 qtrs
Runway
3.7 yrs
3+ years
Net loss
$55.4M
Q2 '26
R&D expense
— of opex
Raised, last 4 qtrs
+$197M
net financing cash flow

Cash & investments

Quarter-end balance

Cash & investments$0$500M$1BQ3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26$497M$540M

Operating cash flow

Per quarter; below zero is burn

Operating cash flow−$50M−$25M$0K$0Q3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26−$44.2M

R&D expense

Per quarter

R&D expense$0$25M$50MQ3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26$33.0M$34.3M

The controller’s read

What the filings say.

Generated from the numbers above using the same questions I ask when I open a client’s books: how long the cash lasts, what is driving the gap between loss and burn, and where the accounting judgment sits.

Get this read on your company

About 3.7 years of runway

Cash and investments of $497M at Q2 '26 against an average operating cash burn of $33.7M per quarter over the last four reported quarters runs out around March 2030. More than two years of runway means the finance conversation is about deployment, not survival.

Cash position down $23.5M since Q3 '24

Net financing inflows of $197M over the last four quarters, from equity, debt, or ATM sales, partly offset operating burn. The balance is the number the board watches; the trend is the number the auditors watch.

Net loss runs $11.2M above cash burn

The Q2 '26 net loss of $55.4M includes non-cash charges, including $8.2M of stock-based compensation, that do not consume cash. Burn, not net loss, is what runway is built on.

Accumulated deficit of $471M

Total losses since inception. It is also roughly the size of the net operating loss carryforward the tax provision has to track, subject to Section 382 limits after each ownership change.

Quarterly detail, eight quarters
QuarterCash & inv.Op. cash flowNet lossR&DG&ARevenueStock compFinancing
Q3 '24 · Sep 29, 24$521M−$17.2M−$17.5M$15.9M$4.8M$2.0M$334M
Q4 '24 · Dec 30, 24$490M−$30.0M−$21.0M$19.9M$6.8M$3.2M−$975K
Q1 '25 · Mar 30, 25$462M−$28.1M−$36.8M$34.3M$7.5M$3.5M$460K
Q2 '25 · Jun 29, 25$437M−$25.6M−$27.4M$24.8M$7.2M$3.5M$135K
Q3 '25 · Sep 29, 25$408M−$29.2M−$36.3M$33.0M$7.7M$3.6M$436K
Q4 '25 · Dec 30, 25$415M−$23.9M−$37.4M$8.1M$4.4M$31.2M
Q1 '26 · Mar 30, 26$540M−$37.5M−$56.2M$12.7M$5.9M$163M
Q2 '26 · Jun 29, 26$497M−$44.2M−$55.4M$14.2M$8.2M$2.3M

Source: SEC EDGAR XBRL company facts, latest filed value for each period. Fourth quarters are derived from annual less nine-month figures; quarterly cash flows are derived from year-to-date amounts. Not investment advice. If a figure disagrees with the filing, the filing is right.