Cambridge biotech tracker · Cambridge

Sarepta Therapeutics

Listed on Nasdaq as SRPT, filed under SEC industry code 2834 (pharmaceutical preparations). Fiscal year ends in December. Numbers below are from the company’s own SEC filings through Q2 '26.

Cash & investments
$934M
Q2 '26 · Jun 29, 2026
Burn per quarter
None
avg. operating cash flow, 4 qtrs
Runway
Self-funding
Self-funding
Net loss
$4.9M
Q2 '26
R&D expense
$91.3M
24% of opex
Raised, last 4 qtrs
−$157M
net financing cash flow

Cash & investments

Quarter-end balance

Cash & investments$0$1B$2BQ3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26$934M$1.49B

Operating cash flow

Per quarter; below zero is burn

Operating cash flow−$1B−$250M$500M$0Q3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26$197M−$583M

R&D expense

Per quarter

R&D expense$0$500M$1BQ3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26$91.3M$773M

The controller’s read

What the filings say.

Generated from the numbers above using the same questions I ask when I open a client’s books: how long the cash lasts, what is driving the gap between loss and burn, and where the accounting judgment sits.

Get this read on your company

Self-funding on an operating basis

Operating cash flow was positive on average over the last four quarters, so runway is not the constraint. Cash and investments stood at $934M at Q2 '26.

Cash position down $446M since Q3 '24

Net financing outflows of $157M over the last four quarters, meaning repayments or buybacks exceeded any new capital. The balance is the number the board watches; the trend is the number the auditors watch.

Net loss runs $202M above cash burn

The Q2 '26 net loss of $4.9M includes non-cash charges, including $24.5M of stock-based compensation, that do not consume cash. Burn, not net loss, is what runway is built on.

R&D is 24% of operating expenses

$91.3M of R&D against $388M of total operating expenses in Q2 '26, with G&A at $108M. For a clinical-stage company, the accounting questions live inside that R&D line: CRO and CMC accruals, milestone recognition, and what gets capitalized versus expensed under ASC 730.

Revenue of $401M in Q2 '26

The balance sheet carries $220M of deferred revenue, which is typically upfront collaboration or license payments being recognized over time. Collaboration and license revenue under ASC 606 and ASC 808 is the single most judgment-heavy area in biotech accounting: performance obligations, variable consideration on milestones, and the split between revenue and cost-sharing.

$848M of long-term debt or convertible notes

Debt in a pre-revenue biotech usually comes with liquidity covenants and, for convertibles, embedded features that need ASC 815 and ASC 470 analysis each quarter.

Accumulated deficit of $4.55B

Total losses since inception. It is also roughly the size of the net operating loss carryforward the tax provision has to track, subject to Section 382 limits after each ownership change.

Quarterly detail, eight quarters
QuarterCash & inv.Op. cash flowNet lossR&DG&ARevenueStock compFinancing
Q3 '24 · Sep 29, 24$1.38B−$70.7M$33.6M$224M$128M$467M$43.5M$13.8M
Q4 '24 · Dec 30, 24$1.49B$92.0M$159M$200M$164M$658M$49.7M$49.0M
Q1 '25 · Mar 30, 25$632M−$583M−$448M$773M$134M$745M$41.4M$12.5M
Q2 '25 · Jun 29, 25$835M$261M$197M$204M$138M$611M$37.0M−$23.8M
Q3 '25 · Sep 29, 25$852M−$14.6M−$50.6M$219M$91.9M$399M$14.9M−$118M
Q4 '25 · Dec 30, 25$941M$131M−$412M$325M$128M$443M−$93.4M−$39.2M
Q1 '26 · Mar 30, 26$735M−$203M$331M$154M$109M$731M$29.4M$241K
Q2 '26 · Jun 29, 26$934M$197M−$4.9M$91.3M$108M$401M$24.5M$0

Source: SEC EDGAR XBRL company facts, latest filed value for each period. Fourth quarters are derived from annual less nine-month figures; quarterly cash flows are derived from year-to-date amounts. Not investment advice. If a figure disagrees with the filing, the filing is right.