Cambridge biotech tracker · Cambridge
Nuvalent
Listed on Nasdaq as NUVL, filed under SEC industry code 2834 (pharmaceutical preparations). Fiscal year ends in December. Numbers below are from the company’s own SEC filings through Q1 '26.
- Cash & investments
- $1.29B
- Q1 '26 · Mar 30, 2026
- Burn per quarter
- $78.2M
- avg. operating cash flow, 4 qtrs
- Runway
- 4.1 yrs
- 3+ years
- Net loss
- $109M
- Q1 '26
- R&D expense
- $83.6M
- 70% of opex
- Raised, last 4 qtrs
- +$521M
- net financing cash flow
Cash & investments
Quarter-end balance
Operating cash flow
Per quarter; below zero is burn
R&D expense
Per quarter
The controller’s read
What the filings say.
Generated from the numbers above using the same questions I ask when I open a client’s books: how long the cash lasts, what is driving the gap between loss and burn, and where the accounting judgment sits.
Get this read on your companyAbout 4.1 years of runway
Cash and investments of $1.29B at Q1 '26 against an average operating cash burn of $78.2M per quarter over the last four reported quarters runs out around May 2030. More than two years of runway means the finance conversation is about deployment, not survival.
Cash position up $629M since Q2 '24
Net financing inflows of $521M over the last four quarters, from equity, debt, or ATM sales, more than covered operating burn. The balance is the number the board watches; the trend is the number the auditors watch.
Net loss runs $16.9M above cash burn
The Q1 '26 net loss of $109M includes non-cash charges, including $28.9M of stock-based compensation, that do not consume cash. Burn, not net loss, is what runway is built on.
R&D is 70% of operating expenses
$83.6M of R&D against $119M of total operating expenses in Q1 '26, with G&A at $35.8M. For a clinical-stage company, the accounting questions live inside that R&D line: CRO and CMC accruals, milestone recognition, and what gets capitalized versus expensed under ASC 730.
Accumulated deficit of $1.08B
Total losses since inception. It is also roughly the size of the net operating loss carryforward the tax provision has to track, subject to Section 382 limits after each ownership change.
Quarterly detail, eight quarters
| Quarter | Cash & inv. | Op. cash flow | Net loss | R&D | G&A | Revenue | Stock comp | Financing |
|---|---|---|---|---|---|---|---|---|
| Q2 '24 · Jun 29, 24 | $658M | −$41.2M | −$57.2M | $49.2M | $16.0M | — | $15.1M | $4.1M |
| Q3 '24 · Sep 29, 24 | $1.17B | −$45.8M | −$84.3M | $60.6M | $15.8M | — | $15.5M | $550M |
| Q4 '24 · Dec 30, 24 | $1.12B | −$62.0M | −$74.8M | $69.4M | $16.9M | — | $16.1M | $8.5M |
| Q1 '25 · Mar 30, 25 | $1.07B | −$54.8M | −$84.6M | $74.4M | $20.4M | — | $20.4M | $4.5M |
| Q2 '25 · Jun 29, 25 | $1.01B | −$76.6M | −$99.7M | $80.9M | $23.7M | — | $22.1M | $5.8M |
| Q3 '25 · Sep 29, 25 | $943M | −$70.5M | −$122M | $83.8M | $28.9M | — | $22.3M | $4.8M |
| Q4 '25 · Dec 30, 25 | $1.37B | −$73.3M | −$119M | $67.8M | $34.4M | — | $21.7M | $500M |
| Q1 '26 · Mar 30, 26 | $1.29B | −$92.4M | −$109M | $83.6M | $35.8M | — | $28.9M | $9.8M |
Source: SEC EDGAR XBRL company facts, latest filed value for each period. Fourth quarters are derived from annual less nine-month figures; quarterly cash flows are derived from year-to-date amounts. Not investment advice. If a figure disagrees with the filing, the filing is right.