Cambridge biotech tracker · Cambridge

Apnimed

Listed on Nasdaq as APMD, filed under SEC industry code 2834 (pharmaceutical preparations). Fiscal year ends in December. Numbers below are from the company’s own SEC filings through Q2 '26.

All companiesFilings on EDGAR Self-fundingGoing concernMaterial weakness
Cash & investments
$173M
Q2 '26 · Jun 29, 2026
Burn per quarter
None
net loss less stock comp
Runway
Self-funding
Self-funding
Net loss
+$126M
Q2 '26 · net income
R&D expense
$9.9M
42% of opex
Raised, last 4 qtrs
$0
net financing cash flow

Cash & investments

Quarter-end balance

Cash & investments$0$100M$200MQ1 '25Q2 '25Q4 '25Q1 '26Q2 '26$173M
Operating cash flow

Not reported in a standard XBRL tag for this company.

R&D expense

Per quarter

R&D expense$0$10M$20MQ1 '25Q2 '25Q4 '25Q1 '26Q2 '26$9.9M$16.0M

The controller’s read

What the filings say.

Generated from the numbers above using the same questions I ask when I open a client’s books: how long the cash lasts, what is driving the gap between loss and burn, and where the accounting judgment sits.

Get this read on your company

Self-funding on an operating basis

Operating cash flow was positive on average over the last four quarters, so runway is not the constraint. Cash and investments stood at $173M at Q2 '26.

Cash position up $131M since Q4 '25

No meaningful financing inflows over the last four quarters, so the change is essentially operating burn. The balance is the number the board watches; the trend is the number the auditors watch.

R&D is 42% of operating expenses

$9.9M of R&D against $23.8M of total operating expenses in Q2 '26, with G&A at $12.7M. For a clinical-stage company, the accounting questions live inside that R&D line: CRO and CMC accruals, milestone recognition, and what gets capitalized versus expensed under ASC 730.

Revenue of $12.1M in Q2 '26

The balance sheet carries $19.5M of deferred revenue, which is typically upfront collaboration or license payments being recognized over time. Collaboration and license revenue under ASC 606 and ASC 808 is the single most judgment-heavy area in biotech accounting: performance obligations, variable consideration on milestones, and the split between revenue and cost-sharing.

Going-concern language in the 10-Q filed Sep 7, 2026

The filing contains definite substantial-doubt language, the conclusion of an ASC 205-40 evaluation that cash may not cover twelve months from the issuance date without additional financing or cost actions. Read the liquidity note in the filing for management's plans and whether they are considered probable.

Material weakness disclosed in the 10-Q filed Sep 7, 2026

Management identified a material weakness in internal control over financial reporting. Common causes at this stage are thin finance teams, manual close processes, and inadequate review of complex areas like revenue or equity. Remediation usually takes two or more quarters to demonstrate.

Stockholders' deficit of $176M

Liabilities exceed assets on the balance sheet. That is common with royalty financings, convertible debt, or large deferred revenue balances, and it is a fact auditors and exchange listing rules both pay attention to.

$40.3M of long-term debt or convertible notes

Debt in a pre-revenue biotech usually comes with liquidity covenants and, for convertibles, embedded features that need ASC 815 and ASC 470 analysis each quarter.

Accumulated deficit of $204M

Total losses since inception. It is also roughly the size of the net operating loss carryforward the tax provision has to track, subject to Section 382 limits after each ownership change.

Cash-only balance shown

This company either holds no marketable securities or tags them under a name the tracker does not read. If the 10-Q reports a larger cash-and-investments figure, that figure is the right one.

Quarterly detail, eight quarters
QuarterCash & inv.Op. cash flowNet lossR&DG&ARevenueStock compFinancing
Q1 '25 · Mar 30, 25−$28.6M
Q2 '25 · Jun 29, 25−$69.5M$16.0M$5.4M$17.1M
Q4 '25 · Dec 30, 25$41.9M
Q1 '26 · Mar 30, 26$67.7M
Q2 '26 · Jun 29, 26$173M$126M$9.9M$12.7M$12.1M

Source: SEC EDGAR XBRL company facts, latest filed value for each period. Fourth quarters are derived from annual less nine-month figures; quarterly cash flows are derived from year-to-date amounts. Not investment advice. If a figure disagrees with the filing, the filing is right.