Cambridge biotech tracker · Newton

Acumen Pharmaceuticals

Listed on Nasdaq as ABOS, filed under SEC industry code 2836 (biological products). Fiscal year ends in December. Numbers below are from the company’s own SEC filings through Q2 '26.

Cash & investments
$110M
Q2 '26 · Jun 29, 2026
Burn per quarter
$22.9M
avg. operating cash flow, 4 qtrs
Runway
14 mo
12 to 24 months
Net loss
$32.7M
Q2 '26
R&D expense
$27.8M
85% of opex
Raised, last 4 qtrs
+$35.5M
net financing cash flow

Cash & investments

Quarter-end balance

Cash & investments$0$250M$500MQ3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26$110M$259M

Operating cash flow

Per quarter; below zero is burn

Operating cash flow−$50M−$25M$0K$0Q3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26−$18.1M−$34.1M

R&D expense

Per quarter

R&D expense$0$25M$50MQ3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26$27.8M$37.1M

The controller’s read

What the filings say.

Generated from the numbers above using the same questions I ask when I open a client’s books: how long the cash lasts, what is driving the gap between loss and burn, and where the accounting judgment sits.

Get this read on your company

About 14 months of runway

Cash and investments of $110M at Q2 '26 against an average operating cash burn of $22.9M per quarter over the last four reported quarters runs out around August 2027. Between one and two years is the window where the next raise gets planned; the terms depend on what the data does before the cash does.

Cash position down $149M since Q3 '24

Net financing inflows of $35.5M over the last four quarters, from equity, debt, or ATM sales, partly offset operating burn. The balance is the number the board watches; the trend is the number the auditors watch.

Net loss runs $14.6M above cash burn

The Q2 '26 net loss of $32.7M includes non-cash charges, including $2.5M of stock-based compensation, that do not consume cash. Burn, not net loss, is what runway is built on.

R&D is 85% of operating expenses

$27.8M of R&D against $32.6M of total operating expenses in Q2 '26, with G&A at $4.7M. For a clinical-stage company, the accounting questions live inside that R&D line: CRO and CMC accruals, milestone recognition, and what gets capitalized versus expensed under ASC 730.

$11.9M of long-term debt or convertible notes

Debt in a pre-revenue biotech usually comes with liquidity covenants and, for convertibles, embedded features that need ASC 815 and ASC 470 analysis each quarter.

Accumulated deficit of $500M

Total losses since inception. It is also roughly the size of the net operating loss carryforward the tax provision has to track, subject to Section 382 limits after each ownership change.

Quarterly detail, eight quarters
QuarterCash & inv.Op. cash flowNet lossR&DG&ARevenueStock compFinancing
Q3 '24 · Sep 29, 24$259M−$24.6M−$29.8M$27.2M$5.0M$2.3M−$42K
Q4 '24 · Dec 30, 24$232M−$27.2M−$37.2M$34.6M$5.0M$2.3M−$9K
Q1 '25 · Mar 30, 25$198M−$34.1M−$28.8M$25.3M$5.1M$2.5M−$36K
Q2 '25 · Jun 29, 25$166M−$31.8M−$41.0M$37.1M$4.6M$2.5M$0
Q3 '25 · Sep 29, 25$136M−$30.5M−$26.5M$22.0M$4.5M$2.5M$0
Q4 '25 · Dec 30, 25$117M−$19.1M−$25.1M$20.5M$4.7M$2.4M$2K
Q1 '26 · Mar 30, 26$128M−$24.1M−$20.7M$16.5M$4.7M$2.4M$35.7M
Q2 '26 · Jun 29, 26$110M−$18.1M−$32.7M$27.8M$4.7M$2.5M−$278K

Source: SEC EDGAR XBRL company facts, latest filed value for each period. Fourth quarters are derived from annual less nine-month figures; quarterly cash flows are derived from year-to-date amounts. Not investment advice. If a figure disagrees with the filing, the filing is right.